Searchable abstracts of presentations at key conferences in endocrinology
ea0050s2.1 | When receptors go rogue | SFEBES2017
Stress and direct targeting of mitochondrial gene expression by the glucocorticoid receptor in the brain
Glucocorticoids (GC) are involved recruiting the energetic response to stress and act principally via the glucocorticoid receptor (GR). The GR is classically understood to function as a nuclear transcription factor. However, the nuclear genome is not the only genome in eukaryotic cells. The mitochondria also contain a small circular chromosome the mitochondrial DNA (mtDNA) that encodes 13 proteins. It has been established that, in the brain and other systems, the...
ea0050s2.1 | When receptors go rogue | SFEBES2017
Stress and direct targeting of mitochondrial gene expression by the glucocorticoid receptor in the brain
Glucocorticoids (GC) are involved recruiting the energetic response to stress and act principally via the glucocorticoid receptor (GR). The GR is classically understood to function as a nuclear transcription factor. However, the nuclear genome is not the only genome in eukaryotic cells. The mitochondria also contain a small circular chromosome the mitochondrial DNA (mtDNA) that encodes 13 proteins. It has been established that, in the brain and other systems, the...
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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